Human Stem Cells Institute OJSC (HSCI) is a Russian public biotech company founded in 2003.

HSCI is engaged in drug discovery, R&D and marketing of innovative proprietary products and services in the field of regenerative medicine, bio-insurance, medical genetics, including reproductive genetics, gene therapy and biopharmaceutics.

The Company aims to foster a new culture of medical care – developing new health care opportunities in such areas as personalized and preventive medicine.

HSCI owns the largest family cord blood stem cell bank in Russia – Gemabank, as well as the reproductive cell and tissue bank Reprobank (personal storage and donation).

The Company launched Neovasculgen®, the first-in-class gene-therapy drug for treating Peripheral Arterial Disease, including Critical Limb Ischemia, and also introduced the innovative cell technology SPRS-therapy, which entails the use of autologous dermal fibroblasts to repair skin damage due to aging and other structural changes.

HSCI is implementing a socially significant project to create its own Russia-wide network of Genetico medical centers & testing lab to provide a range of genetic diagnostic and consulting services with the aim of early identification, prediction and prophylactic treatment of genetic disorders (incl. PGD and NIPT among others).

The Company actively promotes its products on the Russian market and intends to open new markets throughout the world.

HSCI is listed on the Innovation & Investment Market (iIM) of the Moscow Exchange (ticker ISKJ). The Company conducted its IPO in December 2009, becoming the first Russian biotech company to go public.

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Why to use exactly the SPRS therapy but not injections of hyaluronic acid or collagen?

As a matter of fact, both hyaluronic acid and collagen are the skin components responsible for young and healthy skin appearance. In aging skin, the content of these important components is considerably decreased and, for this reason, their inflow from outside can improve the skin condition. However, such an effect has a short-term nature since the used preparations of hyaluronic acid and collagen are synthetic and therefore they are allogenic for the body and, for this reason, they are rapidly destroyed and released from the body. Besides, these preparations (especially those based on collagen) can cause allergic reactions.

The SPRS therapy solves the problem of skin aging by using the absolutely different approach: patient's own fibroblasts are injected into the skin and these fibroblasts naturally and intensively produce all the components that are necessary for the skin youth and they do this for a long time.